A germ cell tumor (GCT) is a neoplasm derived from germ cells. source
A germ cell tumor (GCT) is a neoplasm derived from germ cells.
Germ cell tumors can be cancerous or non-cancerous tumors. source
Germ cell tumors can be cancerous or non-cancerous tumors.
Germ cells normally occur inside the gonads (ovary and testis). source
Germ cells normally occur inside the gonads (ovary and testis).
Germ cell tumors that originate outside the gonads may be birth defects resulting from errors during development of the embryo. source
Germ cell tumors that originate outside the gonads may be birth defects resulting from errors during development of the embryo.
Some investigators suggest that this distribution arises as a consequence of abnormal migration of germ cells during embryogenesis. source
Some investigators suggest that this distribution arises as a consequence of abnormal migration of germ cells during embryogenesis.
Others hypothesize a widespread distribution of germ cells to multiple sites during normal embryogenesis. source
Others hypothesize a widespread distribution of germ cells to multiple sites during normal embryogenesis.
Of all anterior mediastinal tumors, 15-20% are germ cell tumors of which approximately 50% are benign teratomas. source
Of all anterior mediastinal tumors, 15-20% are germ cell tumors of which approximately 50% are benign teratomas.
Germ cell tumors are classified by their histology, regardless of location in the body. source
Germ cell tumors are classified by their histology, regardless of location in the body.
Germ cell tumors are broadly divided in two classes. source
Germ cell tumors are broadly divided in two classes.
The germinomatous or seminomatous germ cell tumors (GGCT, SGCT) include only germinoma and its synonyms dysgerminoma and seminoma. source
The germinomatous or seminomatous germ cell tumors (GGCT, SGCT) include only germinoma and its synonyms dysgerminoma and seminoma.
The nongerminomatous or nonseminomatous germ cell tumors (NGGCT, NSGCT) include all other germ cell tumors, pure and mixed. source
The nongerminomatous or nonseminomatous germ cell tumors (NGGCT, NSGCT) include all other germ cell tumors, pure and mixed.
In females, germ cell tumors account for 30% of ovarian tumors, but only 1 to 3% of ovarian cancers in North America. source
In females, germ cell tumors account for 30% of ovarian tumors, but only 1 to 3% of ovarian cancers in North America.
In males, germ cell tumors of the testis occur typically after puberty and are malignant (testicular cancer). source
In males, germ cell tumors of the testis occur typically after puberty and are malignant (testicular cancer).
Males with Klinefelter syndrome have a 50 times greater risk of germ cell tumors (GSTs). source
Males with Klinefelter syndrome have a 50 times greater risk of germ cell tumors (GSTs).
Women with benign germ cell tumors such as mature teratomas (dermoid cysts) are cured by ovarian cystectomy or oophorectomy. source
Women with benign germ cell tumors such as mature teratomas (dermoid cysts) are cured by ovarian cystectomy or oophorectomy.
In general, all patients with malignant germ cell tumors will have the same staging surgery that is done for epithelial ovarian cancer. source
In general, all patients with malignant germ cell tumors will have the same staging surgery that is done for epithelial ovarian cancer.
Most patients with germ cell cancer will need to be treated with combination chemotherapy for at least 3 cycles. source
Most patients with germ cell cancer will need to be treated with combination chemotherapy for at least 3 cycles.
The 1997 International Germ Cell Consensus Classification is a tool for estimating the risk of relapse after treatment of malignant germ cell tumor. source
The 1997 International Germ Cell Consensus Classification is a tool for estimating the risk of relapse after treatment of malignant germ cell tumor.
Choriocarcinoma of the testicles has the worst prognosis of all germ cell cancers. source
Choriocarcinoma of the testicles has the worst prognosis of all germ cell cancers.
Intracranial Germ Cell Tumors have been studied through the International CNS GCT Study Group. source
Intracranial Germ Cell Tumors have been studied through the International CNS GCT Study Group.